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Critical Care: Fellow Case Report Poster - Critical Care II |

Thiamine: An Underutilized Agent in Refractory Lactic Acidosis

Ismini Kourouni, MD; Stefania Pirrotta, MD; Joseph Mathew, MD; Janet Shapiro, MD
Author and Funding Information

Mount Sinai West, New York, NY


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4_S):247A. doi:10.1016/j.chest.2016.08.260
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SESSION TITLE: Fellow Case Report Poster - Critical Care II

SESSION TYPE: Affiliate Case Report Poster

PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM

INTRODUCTION: Lactic acid (LA) is a biomarker of unparalleled use in critical care practice,mainly by serving as index of perfusion and outcome predictor in circulatory and septic shock.Thiamine deficiency(TD) is an underappreciated cause of lactic acidosis in critically ill patients. Relative or absolute TD may occur de novo or develop rapidly in settings of low intake, sepsis, critical illness, alcoholism, malabsorptive states or psychiatric problems. We present a case of severe non-shock related lactic acidosis that resolved after high-dose thiamine administration.

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