SESSION TITLE: Student/Resident Case Report Poster - Chest Infections II
SESSION TYPE: Student/Resident Case Report Poster
PRESENTED ON: Tuesday, October 25, 2016 at 01:30 PM - 02:30 PM
INTRODUCTION: Whipple disease (WD) is a rare multisystemic illness caused by the gram positive rod Tropheryma whipplei. Its prevalence is difficult to estimate but approximately one thousand cases have been reported with a frequency of 0.1% in postmortem studies. 15% of patients with WD present with wide variability of symptoms making it a diagnostic challenge. Pulmonary involvement has an estimated prevalence of 30% to 40% with mediastinal adenopathy being reported in 12% of cases. The reactive macrophages which occur in nonspecific lesions are sometimes Periodic-acid Schiff (PAS) negative and do not contain T. whipplei and this presents a diagnostic challenge.