CASE PRESENTATION: The patient is a 34-year-old male with a history of CF complicated by pancreatic insufficiency and diabetes, who was referred for transplant evaluation for progressive decline in FEV1 and recurrent CF exacerbations. He was listed for transplant until BCC was isolated from the sputum and he was placed on hold. Testing at the reference lab in Michigan confirmed the species to be B. seminalis. The patient was re-activated and underwent successful lung transplant several months later. He was treated perioperatively with broad-spectrum antibiotics including inhaled tobramycin. He is now 4 months post-transplant and remains stable without signs of rejection or serious illness though his cultures continue to grow BCC.