SESSION TITLE: Asthma
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Monday, October 24, 2016 at 01:30 PM - 02:30 PM
PURPOSE: To compare treatment satisfaction with inhaled therapy among asthmatics using metered dose inhaler (MDI) or dry powder inhaler (DPI), and to correlate it with treatment adherence, lung function, and airway inflammation.
METHODS: 200 adult patients of asthma (69 men and 131 women) using MDI or DPI regularly for at least one year were enrolled after obtaining informed consent. Pregnant women and patients with coexisting medical conditions that could potentially impair level of activity or worsen quality of life were excluded. Spirometry was performed, and Fractional Expired nitric oxide (FeNO) concentration was measured orally, for all patients. Asthma control was assessed as per Global Initiative Against Asthma (GINA) guidelines. Medication Adherence Questionnaire (MAQ) was used to evaluate adherence to treatment on a scale of 0-4, with higher scores indicating better adherence. Treatment satisfaction with inhaled therapy was assessed through the Hindi version of 14-item Treatment Satisfaction Questionnaire for Medication (TSQM, version 1.4) in four domains - Effectiveness, Side effects, Convenience and Global Satisfaction, on a scale of 0-100, with higher scores implying greater satisfaction. Group differences for TSQM domain scores between MDI and DPI users were evaluated through an analysis of covariance (ANCOVA) model with MAQ score as covariate.