Allergy and Airway: Allergy - Asthma |

Prevalence of Asthma-COPD Overlap Syndrome (ACOS) in Patients Previously Diagnosed as COPD in Ilorin, Nigeria FREE TO VIEW

Olufemi Desalu, MBChB; Olutobi Ojuawo, MBBS; Ademola Fawibe, MBBS; Adeniyi Aladesami, MBBS
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Department of Medicine University of Ilorin, Ilorin, Nigeria

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;150(4_S):4A. doi:10.1016/j.chest.2016.08.007
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SESSION TITLE: Allergy - Asthma

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM

PURPOSE: To determine prevalence of Asthma -COPD overlap syndrome among patients previously diagnosed as COPD in Ilorin, Nigeria

METHODS: This was a retrospective study of patients with chronic airway disease (asthma or COPD) between 2010 and 2015 that attended a respiratory clinic in Ilorin Nigeria. We carried out a chart review of cases with diagnosis of chronic airway diseases. GINA syndromic definition of airway disease was used in identifying cases of ACOS.

RESULTS: A total of 184 patients with chronic airway disease with complete clinical data were reviewed, 93 (50.5%) were males while 91 (49.5%) were females. Seventy four (40.2 %) had asthma and 110 (59.8 %) had COPD. The prevalence of ACOS among patients with chronic airway disease was 4.9% and it was 8.2% among those previously diagnosed with COPD. The mean age of patients with ACOS was 58.4± 8.6 with a median duration of illness of 7.5 years (interquartile range 3-23). Five of the patients with ACOS were males, had history of tobacco smoking and use of biomass fuel for cooking respectively. One third (33.3 %) of the patients had history of occupational exposure to dust and chemical irritants. In terms of pattern of symptoms, 2 had predominantly asthma symptoms and 3 had predominantly COPD symptoms while 4 had overlapping symptoms of asthma and COPD.

CONCLUSIONS: Nearly one in ten patients previously diagnosed as COPD had Asthma -COPD overlap syndrome in this study. The result may have an implication on the management of this condition and may also serve as a template for future epidemiological studies.

CLINICAL IMPLICATIONS: ACOD is associated with increased morbidity and mortality with a more rapid decline in lung function. This study will allow patients with asthma-COPD overlap to be identified earlier and provided with appropriate treatment and support

DISCLOSURE: The following authors have nothing to disclose: Olufemi Desalu, Olutobi Ojuawo, Ademola Fawibe, Adeniyi Aladesami

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