Focused point-of-care TTE was done in this case (see Video 3) to investigate the etiology of the patient’s hypoxia and new-onset hypotension. The TTE immediately revealed left ventricular (LV) dysfunction. With further careful investigation, regional wall motion abnormalities (RWMAs) were noted in the parasternal short-axis view of the left ventricle at the mid-papillary level. Although the parasternal short-axis view of the left ventricle showed septal, inferior, and lateral wall motion abnormalities, the apex was not visualized in this view. Point-of-care TTE, while focused, should allow for full visualization of both ventricles during the investigation of unexplained hypotension and hypoxia. Preserved LV apical function was noted only after obtaining the subcostal four-chamber view, one that allows for visualization of the apex. Collectively, Videos 1 and 2 revealed a dilated inferior vena cava, depressed LV function with RWMAs, and apical sparing. There were no ST-T segment changes seen on the ECG, but troponin I was elevated to 8.9 ng/mL. Initiation of epinephrine infusion rapidly improved her hypotension, hypoxia, and cardiac function. Follow-up troponin I levels were down-trending. Formal TTE on day 2 confirmed reduced LV systolic function, with an estimated ejection fraction of 45% and inferior, lateral, and septal wall motion abnormalities. The patient received a diagnosis of neurogenic stress cardiomyopathy (NSCM) and continued receiving supportive measures with mechanical ventilation and ionotropic support. After aneurysm coiling, the patient continued to improve, with an increased ejection fraction to 54% on day 3. By day 5, she was weaned off epinephrine, following commands, and extubated with minimal oxygen requirements.