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Recent Advances in Chest Medicine |

Surgical lung biopsy for interstitial lung diseases

Rishi Raj, MD; Kirtee Raparia, MD; David A. Lynch, MD; Kevin K. Brown, MD
Author and Funding Information

Funding: None

COI Statement: There are no conflict of interest as it pertains to the current manuscript for Rishi Raj, Kirtee Raparia, David Lynch and Kevin Brown.

1Northwestern University, Chicago IL, USA

2National Jewish Health, Denver CO, USA

Corresponding author: Rishi Raj, MD 676 N. St. Clair, Ste.1400 Chicago, IL 60611, USA.


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016. doi:10.1016/j.chest.2016.06.019
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Abstract

This review addresses common questions regarding the role of surgical lung biopsy in the diagnosis and treatment of interstitial lung disease (ILD). We specifically address when a surgical lung biopsy (SLB) can be diagnostic as well as when it may be avoided, e.g., when the combination of the clinical context and the imaging pattern seen on high resolution CT (HRCT) chest can provide a confident diagnosis. Existing studies on the diagnostic utility as well as the complications associated with SLB are reviewed; as are the performance characteristics and reliability of HRCT scan of the chest in predicting the underlying histopathology of the lung. The review is formatted in the form of answers to questions that clinicians regularly ask when considering SLB in a patient with ILD.


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