We agree with Raimondi et al that a multicenter, prospective study would greatly aid in the reliability and accuracy of findings regarding the use of ultrasound in the diagnosis of lung disease. However, such a study may lead to other issues because, first, “gold standards” diagnostic criteria do not always result in a correct diagnosis (eg, RDS). According to Neonatal Respiratory Disorder, 77% of cases diagnosed as RDS are actually TTN. Thus, the use of traditional diagnostic criteria results in a high misdiagnosis rate for neonatal lung diseases. Traditionally, RDS was considered to be pathologically characterized by atelectasis caused by pulmonary surfactant deficiency, and this condition manifests on chest radiograph as a uniform reduction in light permeability or ground-glass or “white lung” changes in the lungs. However, lung ultrasound findings have greatly changed the characterization of RDS., Atelectasis or lung consolidation may dominate one side while pulmonary edema dominates the other side, or edema and/or effusion may dominate one lobe while lung consolidation dominates another lobe. Lung lesions of varying nature and severity may be present on the same side as atelectasis, lung consolidation, edema, and/or effusion or on the opposite side. Second, we cannot be sure that the diagnostic accuracy would always be the same if lung ultrasound was performed by different operators in the same or different medical centers, whereas our center has enough cases to complete such kinds of clinical investigations.