0
Special Features |

Cystic Lung Diseases: Algorithmic Approach

Suhail Raoof, MD; Praveen Bondalapati, MD; Ravikanth Vydyula, MD; Jay H. Ryu, MD; Nishant Gupta, MD; Sabiha Raoof, MD; Jeff Galvin, MD; Mark J. Rosen, MD; David Lynch, MD; William Travis, MD; Sanjeev Mehta, MD; Richard Lazzaro, MD; David Naidich, MD
Author and Funding Information

aPulmonary Division, Lenox Hill Hospital

bPulmonary Division, Lourdes Hospital

cPulmonary Critical Care Division, Lenox Hill Hospital

dPulmonary/CCM, Mayo Clinic

ePulmonary, Critical Care and Sleep Medicine, University of Cincinnati

fDepartment of Radiology, Jamaica Hospital

gDepartment of Radiology, University of Maryland

hPulmonary, Critical Care and Sleep Medicine, North Shore University Hospital

iDepartment of Radiology, National Jewish Health

jDepartment of Pathology, Memorial Sloan Kettering Cancer Center

kPulmonary Division, Lilavati Hospital

lDepartment of Thoracic Surgery, Lenox Hill Hospital, Northwell Health

mDepartment of Radiology, NYU–Langone Medical Center

CORRESPONDENCE TO: Suhail Raoof, MD, Division of Pulmonary Medicine, Achilles 3 Bldg, Lenox Hill Hospital, 130 E 77th St, New York, NY 10075


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;150(4):945-965. doi:10.1016/j.chest.2016.04.026
Text Size: A A A
Published online

Cysts are commonly seen on CT scans of the lungs, and diagnosis can be challenging. Clinical and radiographic features combined with a multidisciplinary approach may help differentiate among various disease entities, allowing correct diagnosis. It is important to distinguish cysts from cavities because they each have distinct etiologies and associated clinical disorders. Conditions such as emphysema, and cystic bronchiectasis may also mimic cystic disease. A simplified classification of cysts is proposed. Cysts can occur in greater profusion in the subpleural areas, when they typically represent paraseptal emphysema, bullae, or honeycombing. Cysts that are present in the lung parenchyma but away from subpleural areas may be present without any other abnormalities on high-resolution CT scans. These are further categorized into solitary or multifocal/diffuse cysts. Solitary cysts may be incidentally discovered and may be an age related phenomenon or may be a remnant of prior trauma or infection. Multifocal/diffuse cysts can occur with lymphoid interstitial pneumonia, Birt-Hogg-Dubé syndrome, tracheobronchial papillomatosis, or primary and metastatic cancers. Multifocal/diffuse cysts may be associated with nodules (lymphoid interstitial pneumonia, light-chain deposition disease, amyloidosis, and Langerhans cell histiocytosis) or with ground-glass opacities (Pneumocystis jirovecii pneumonia and desquamative interstitial pneumonia). Using the results of the high-resolution CT scans as a starting point, and incorporating the patient’s clinical history, physical examination, and laboratory findings, is likely to narrow the differential diagnosis of cystic lesions considerably.


Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
Diffuse Cystic Lung Diseases*: Correlation Between Radiologic and Functional Status
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543