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Sleep Disorders: Sleep Disorders II |

Liver Enzymes and Lipid Profile in Han Chinese Subjects With Obstructive Sleep Apnea

Chenjuan Gu, PhD; Qing Yun Li, PhD; Min Li, MD; Jun Zhou, MD; Juan Du, MD; Huahua Yi
Author and Funding Information

Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medcine, Shanghai, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A574. doi:10.1016/j.chest.2016.02.599
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SESSION TITLE: Sleep Disorders II

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To explore the association of obstructive sleep apnea (OSA) with liver enzymes and lipid profile in Han Chinese subjects.

METHODS: A total of 172 Han Chinese subjects, 133 men and 39 women, aged from 18 to 69 years with an average body mass index (BMI) of (33.51±5.90) kg/m2 were enrolled and divided into three groups based on full-night polysomnography (PSG): severe OSA group (AHI>30 events/h), mild to moderate OSA group (5<AHI≤30 events/h) and control group (AHI<5 events/h). Liver enzymes and lipid profile were measured after an overnight fast. Measurements were compared among groups by one-way analysis of variance (ANOVA). Stepwise multiple linear regressions were conducted to determine the independent linear correlation of liver enzymes and lipid profile with PSG parameters.

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