Sleep Disorders: Sleep Disorders I |

Polysomnography Improves the Success Rate of Noninvasive Ventilation in Obesity Hypoventilation Syndrome Complicated With Respiratory Failure and Heart Failure FREE TO VIEW

Mengge Wang, MD; Songyun Ouyang; Jiao Su; Peizong Sun; Linge Sun; Ruiying Chen; Hongmin Wang
Author and Funding Information

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A561. doi:10.1016/j.chest.2016.02.586
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SESSION TITLE: Sleep Disorders I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Noninvasive mechanical ventilation (NIMV) is the preferred treatment strategy in patients with obesity hypoventilation syndrome (OHS) complicated with Respiratory failure (RF) and heart failure (HF), but because of high failure rate of initial NIMV in severe patients, most reported cases were eventually forced into invasive mechanical ventilation (IMV). We aimed to use the PSG monitoring to explore a new method of NIMV to avoid IMV.

METHODS: We retrospectively analyzed 46 cases in January 2006 and October 2014. They were in a critical condition and immediately treated by bi-level positive pressure ventilation (BPPV) on addmission. 23 cases underwent BPPV without PSG named group non-PSG, and the rest 23 cases underwent BPPV under PSG named group PSG.

RESULTS: In the starting 7h, inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP) increased gradually and had no obvious statistical difference in the two groups between 1h to 2h. But during 2h to 3h, PaCO2 increased and minimum pulse oxygen saturation (L-SpO2) declined dramatically in group non-PSG. Then IPAP, EPAP and L-SpO2 in group non-PSG were lower than that of group PSG. During hospitalization, the intubation rate, total hospital mortality, length of stay (LOS) and the toal cost in group PSG were lower than that of group non-PSG, and the difference was statistically significant.

CONCLUSIONS: PSG monitoring improves improves the success rate of NIMV in OHS complicated with RF and HF.

CLINICAL IMPLICATIONS: PSG monitoring improves improves the success rate of NIMV in OHS complicated with RF and HF.

DISCLOSURE: The following authors have nothing to disclose: Mengge Wang, Songyun Ouyang, Jiao Su, Peizong Sun, Linge Sun, Ruiying Chen, Hongmin Wang

no additional information.




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