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Pulmonary Vascular Disease: Pulmonary Vascular Disease: VTE |

Predictive Value of the High-Sensitivity Troponin I Assay in Patients With Acute Pulmonary Embolism

Xin Xi, MD
Author and Funding Information

Beijing Anzhen Hospital, Capital Medical University, Beijing, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A525. doi:10.1016/j.chest.2016.02.547
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Extract

SESSION TITLE: Pulmonary Vascular Disease: VTE

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To evaluate the predictive value of the high-sensitivity cardiac troponin I (hs-cTnI) assay in patients with acute pulmonary embolism (APE).

METHODS: In a retrospective cohort study, 272 consecutive patients with APE were reviewed and the 30-days death and in-hospital adverse events were evaluated. The patients were classified according to hs-cTnI value into high hs-cTnI group and low hs-cTnI group. The simple Pulmonary Embolism Severity Index (sPESI) was used for clinical risk determination. The adverse events was defined as intravenous thrombolytic therapy, noninvasive ventilator support to maintain oxygen saturation > 90% and suffered with severe complications. The correlations of hs-cTnI with sPESI score, 30-days adverse events and mortality were analyzed. The Kaplan-Meyer curves and the log-rank test were used to compare time-to-event survival. Stepwise multivariate logistic regression analysis models were used to determine the incremental prognostic value of PESI score and hs-cTnI.

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