Pulmonary Vascular Disease: Pulmonary Vascular Disease: VTE |

Clinical Characteristics and Risk Factors of Pulmonary Embolism in Adults Due to Mycoplasma Pneumoniae Pneumonia FREE TO VIEW

Ze-Ying Liu; Shuang Liu; Jin-Hua Liu
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Beijing Anzhen Hospital, Capital Medical Uninversity, Beijing Institute of Heart Lung & Blood Vessel Disease, Beijing, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A520. doi:10.1016/j.chest.2016.02.542
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SESSION TITLE: Pulmonary Vascular Disease: VTE

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Despite of several case report of the adults’ pulmonary embolism due to mycoplasma pneumoniae pneumonia, there were few clinical trials focusing on the diseases’ feature. Therefore, we conducted this study to investigate the clinical characteristics and risk factors of adults’ pulmonary embolism due to mycoplasma pneumoniae pneumonia.

METHODS: Case-controlled observational cohort was observed in a single center. From September 2009 to June 2014, 697 consecutive patients with mycoplasma pneumoniae pneumonia were involved. 47 patients with pulmonary embolism due to mycoplasma pneumoniae pneumonia were compared to 94 consecutive age-matched patients with only mycoplasma pneumoniae pneumonia. Clinical and laboratory data were obtained.

RESULTS: Patients with pulmonary embolism due to mycoplasma pneumoniae pneumonia had more severe clinical profiles at admission. Serious chest pain, dyspnea, pulmonary hypertension,bloody pleural effusion were much more common in patients with pulmonary embolism. Multivariate logistic regression analysis showed mycoplasma antibody (IgM)>1:320, positive antiphospholipid antibody,decreased levels of protein C and protein S, elevated levels of fibrinogen and D-dimer in plasma were risk factors associated with higher morbidity of pulmonary embolism in patients with mycoplasma pneumoniae pneumonia.

CONCLUSIONS: Mycoplasma pneumoniae pneumonia in adults increase the incidence of activating the coagulation system and inducing pulmonary embolism subsequently.

CLINICAL IMPLICATIONS: Patients who present with mycoplasma pneumoniae pneumonia infections should be monitored closely for signs of thrombosis and should be anti-coagulated appropriately.

DISCLOSURE: The following authors have nothing to disclose: Ze-Ying Liu, Shuang Liu, Jin-Hua Liu

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