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Pulmonary Vascular Disease: Pulmonary Vascular Disease: PAH |

The Establishment of Acute Pulmonary Embolism Model in Rabbit

Zhang Xiaoqin
Author and Funding Information

Inner Mongolia People's Hospitai, Hohhot, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A513. doi:10.1016/j.chest.2016.02.535
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SESSION TITLE: Pulmonary Vascular Disease: PAH

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Study the feasibility of manufacturing the model of acute pulmonary embolism by injecting gelatin sponge from New Zealand rabbit ear margin vein.

METHODS: 24 New Zealand rabbits divided into two groups: experimental group (n=22) and control group (n=2). In experimental group, we injected gelatin sponge into rabbit’s ear margin vein, and divided them into 2 houes, 1 day, 3 days, 7 days group. All proceed CTPA and lung perfusion examination before and after embolization. After the inspection, all rabbits put to death. Control group injected isotonic saline into rabbit’s ear margin vein. After the inspection, all rabbits put to death. All groups put to pathological examination.

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