Pulmonary Vascular Disease: Pulmonary Vascular Disease: PAH |

Idiopathic Hypereosinophilic Syndrome With Pulmonary Arterial Hypertension: A Case Report and Literature Review FREE TO VIEW

Lin Liu, DrPH; Xianwei Ye, DrPH; Xiangyan Zhang, MS
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Guizhou Provincial People's Hospital, Guiyang, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A512. doi:10.1016/j.chest.2016.02.534
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SESSION TITLE: Pulmonary Vascular Disease: PAH

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To describe the clinical features, auxiliary examinations and treatment of idiopathic hypereosinophilic syndrome (IHES) with pulmonary arterial hypertension (PAH).

METHODS: The diagnosis and treatment process of one case of IHES with PAH had been retrospectively analyzed. Literatures were retrieved with ‘idiopathic hypereosinophilic syndrome’ and ‘pulmonary arterial hypertension' from PubMed, China National Knowledge Infrastructure (CNKI), Wanfang Data and VIP data, of which all the literatures about IHES were reviewed.

RESULTS: The 26-year-old man was admitted for cough and dyspnea for more than 7 months. Routine blood test showed that the WBC was 13.73×109/L and eosinophilia was 57.5%. CT showed the multiple lesions in both lungs and bilateral pleural effusion. Echocardiogram indicated PAH, mitral valve regurgitation and tricuspid valve regurgitation. Lung biopsy showed that the eosinophil infiltrated alveolar septa and alveolar. The diagnosis of IHES was considered. Glucocorticoids and vasodilators applied, the patient discharged with the improvement of symptoms and signs. No Chinese article was found and one English literature was obtained which was a case report.

CONCLUSIONS: PAH as the outstanding performance of IHES is relatively rare. Early recognition and aggressive treatment can help improve the patients outcomes.

CLINICAL IMPLICATIONS: Idiopathic hypereosinophilic syndrome (IHES) with pulmonary arterial hypertension (PAH) is relatively rare. Early recognition and aggressive treatment is necessary and inportant.

DISCLOSURE: The following authors have nothing to disclose: Lin Liu, Xianwei Ye, Xiangyan Zhang

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