Pulmonary Rehabilitation: Pulmonary Rehabilitation |

Ultrasonographic Echo Intensity of the Quadriceps in Chronic Obstructive Pulmonary Disease Patients: A Pilot Study FREE TO VIEW

Xiong Ye, MD; Hui Xiao, MD; SuiYang Zhang, MD; Lundbäck Bo, PhD
Author and Funding Information

Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A493. doi:10.1016/j.chest.2016.02.514
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SESSION TITLE: Pulmonary Rehabilitation

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: We investigated whether echo intensity of quadriceps measured by ultrasound can distinguish muscles affected by chronic obstructive pulmonary disease (COPD) from healthy muscles and whether severity of ultrasound abnormalities is associated with health-related quality of life (HRQL).

METHODS: Echo intensity, thickness and areas of the quadriceps muscles using ultrasound were measured in 50 patients with COPD and 21 non-COPD controls.

RESULTS: There were significantly higher echo intensity of the rectus femoris in all stages of COPD patients than in age-matched non-COPD subjects, the quadriceps muscle thickness and rectus femoris cross-sectional area significantly decreased in COPD GOLD III∼IV only. In COPD patients, echo intensity of the rectus femoris associated with HRQL independently.

CONCLUSIONS: Quantitative ultrasound distinguishes healthy muscles from those affected by COPD gradeⅠ~ Ⅳ, measures of muscle quality and quantity are associated with HRQL and FEV1. Ultrasound echo intensity of the rectus femoris may be a useful tool for assessing disease severity and monitoring the changes of skeletal muscle resulting from disease progression or clinical intervention in patients with COPD.

CLINICAL IMPLICATIONS: Quantitative analysis of ultrasonic echo intensity of skeletal muscle in COPD patients may reflect the changes of its structure and function change early.

DISCLOSURE: The following authors have nothing to disclose: Xiong Ye, Hui Xiao, SuiYang Zhang, Lundbäck Bo

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