Pulmonary Physiology: Pulmonary Physiology |

Correction Factor Between Difference Ethnic Groups in Spirometry FREE TO VIEW

Wenhua Jian, MD; Yi Gao, MD; Wei-jie Guan, PhD; Mei Jiang, PhD; Nanshan Zhong, MD; Jin-ping Zheng, MD
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First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A481. doi:10.1016/j.chest.2016.02.501
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SESSION TITLE: Pulmonary Physiology

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Many areas and ethnic groups lack their own spirometer reference values. Caucasian reference values adjusted with a fixed ethnic correction factor were recommended for these areas and ethnic groups, while this method was doubted. This study was to investigate the feasibility of a fixed ethnic correction factor for spirometry between Caucasian and Chinese.

METHODS: The health Caucasian data (including age, gender, height, and FEV1) were derived from global lung function initiative while health Chinese data were taken from the nationwide Chinese lung function study. The percentage differences of height, FEV1, and adjusted FEV1 between Chinese and Caucasian as a function of age were calculated as “(Caucasian-Chinese) /Chinese*100%”.

RESULTS: There were a total of 6661 Chinese (51.1% females) and 12741 Caucasian (55.2% females), respectively. In term of height, the difference between Caucasian and Chinese is -1.1%∼4.6%, relatively steady in adult age, while a “V” variation in childhood. In FEV1 and FEV1 adjusted with height, the difference between Caucasian and Chinese -5.4%∼18.4% and -6.9%∼5.9%, only steady in part of the adult age, while a “V” variation still in childhood. Among adult age and childhood, the percentage differences of FEV1 adjusted with height between Caucasian and Chinese changed great (beyond ±5%, the acceptable limit) and its trends were inconsistent.

CONCLUSIONS: There was not a suitable ethnic correction factor for spirometry between Caucasian and Chinese.

CLINICAL IMPLICATIONS: Fixed ethnic correction factor might not be applied for different ethnic groups, and needed further research.

DISCLOSURE: The following authors have nothing to disclose: Wenhua Jian, Yi Gao, Wei-jie Guan, Mei Jiang, Nanshan Zhong, Jin-ping Zheng

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