RESULTS: From January to August 2015, 10 consecutive patients (median age 71 years) were referred for a MPE due to pneumonia in 6 cases, empyema in 3 cases, infected hemothorax in 1 case. Median time from diagnosis to chest drain was 2 months. Two patients required 8 and 9 days of intrapleural treatment due to positive coltures on pleural fluid and persistent sistemic infection respectively. No patients required surgical intervention. In 9 cases, MPE disappeared within one month from the first treatment. A persistent collection was recorded in the hemothorax case, with negative coltures at the time of drain removal.