RESULTS: During this period, there were 61 patients undergoing pleuradesis. 41 of them recieved thorascopic talc poudrage (Group A), whereras the left underwent pleuradesis by iodophor (Group B). The average age was 65.85±13.76 years and 71.35±9.75 years respectively (P=0.175). The sexual composition has no difference (Group A,19 females:22 males, Group B,6 females: 14 males, P=0.223). None of them had allergic reaction or defect of visual field. There’s no significant difference in the incidence of chest pain (36.6% vs.40%, p=0.796) or hypotension (4.9% vs. 10%, P=0.448). Four patients experienced arhythima in Group A, but none in Group B. Patients in both groups had fever (68.3% vs. 80%, P=0.338) and white blood cell elevation (2.9×109/L vs. 2.3×109/L, P=0.637) after the procedure, but there’s no significant difference. Both group had similar success rate in pleuradesis (80.5%vs.90%, P=0.346), with no reaccumulation of fluid before discharging. Time for withdrawing the chest tube was 6[2, 14] days and 3.5[1,21] days respectively, with no significant difference.