Procedures: Procedures: Pleura |

Talc Poudrage vs Iodophor in Pleurodesis FREE TO VIEW

Junfang Huang, MD; Ying Liu, MD; Hong Zhang, MD; Guangfa Wang, MD
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Pecking University First Hospital, Beijing, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A438. doi:10.1016/j.chest.2016.02.456
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SESSION TITLE: Procedures: Pleura

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: The purpose was to compare the safety and outcome of iodophor pleurodesis with thoracscopic talc poudrage pleurodesis.

METHODS: Patients who underwent pleuradesis in Respiratory Department in Pecking university first hospital during 2005 to 2015 were selected. A retrospective analysis of postoperative complications, effecacy was performed.

RESULTS: During this period, there were 61 patients undergoing pleuradesis. 41 of them recieved thorascopic talc poudrage (Group A), whereras the left underwent pleuradesis by iodophor (Group B). The average age was 65.85±13.76 years and 71.35±9.75 years respectively (P=0.175). The sexual composition has no difference (Group A,19 females:22 males, Group B,6 females: 14 males, P=0.223). None of them had allergic reaction or defect of visual field. There’s no significant difference in the incidence of chest pain (36.6% vs.40%, p=0.796) or hypotension (4.9% vs. 10%, P=0.448). Four patients experienced arhythima in Group A, but none in Group B. Patients in both groups had fever (68.3% vs. 80%, P=0.338) and white blood cell elevation (2.9×109/L vs. 2.3×109/L, P=0.637) after the procedure, but there’s no significant difference. Both group had similar success rate in pleuradesis (80.5%vs.90%, P=0.346), with no reaccumulation of fluid before discharging. Time for withdrawing the chest tube was 6[2, 14] days and 3.5[1,21] days respectively, with no significant difference.

CONCLUSIONS: Iodophor plurodesis had similar outcome compared with thoracscopic talc poudrage pleurodesis. Iodophor was as safe as talc poudrage in the procedure.

CLINICAL IMPLICATIONS: Iodophor was more readily and inexpensive in clincal practice, it can be a good optional agent in pleurodesis.

DISCLOSURE: The following authors have nothing to disclose: Junfang Huang, Ying Liu, Hong Zhang, Guangfa Wang

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