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Procedures: Procedures: Bronchoscopy |

Diagnostic Value of EBUS-TBNA vs C-TBNA in the Diagnosis of Mediastinal Masses: A Systematic Review and Meta-analysis

Lei Pan, PhD; Guo-Gang Xu, PhD; Jun Guo, PhD; Yongzhong Guo; Changting Liu
Author and Funding Information

Affiliated Hospital of Binzhou Medical University, Chinese PLA General Hospital, Binzhou, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A434. doi:10.1016/j.chest.2016.02.452
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SESSION TITLE: Procedures: Bronchoscopy

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To evaluate the diagnostic value of endobronchial ultrasound vs. conventional transbronchial needle aspiration in the diagnosis of mediastinal masses.

METHODS: Computer-based retrieval was performed on PubMed, EMBASE, Cochrane Library, CBM, and CNKI (up to Apr 2015). Randomized controlled trials that compared conventional transbronchial needle aspiration (C-TBNA) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of patients with mediastinal masses were included. The quality of included trials was evaluated according to quality assessment of diagnostic accuracy studies-2 (QUADAS-2), and MetaDisc software (Version 1.4) was adopted to perform meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) were calculated. The summary receiving operating characteristic (SROC) curve as well as the areas under curve (AUC) was measured.

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