State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
Copyright 2016, American College of Chest Physicians. All Rights Reserved.
SESSION TITLE: Bronchology
SESSION TYPE: Case Report Slide
PRESENTED ON: Sunday, April 17, 2016 at 02:15 PM - 03:45 PM
INTRODUCTION: Bronchial thermoplasty (BT), which involves the delivery of radio frequency energy to the bronchial tree to reduce airway smooth muscle quantity and contractility, has been latterly bring in the treatment of severe refractory asthma. Follow-up data to date support the safety of the procedure. Atelectasis and Lung abscess after BT in severe asthma has been described in literature, but bronchiectasis has never been reported as a direct complication of BT.
CASE PRESENTATION: A forty nine year old Asian male has 2 years serve asthma, accompanied diabetes mellitus. His several times of chest CT scan is normal before BT. A month after BT he presented mild bronchiectasia in HRCT with yellow purulent sputum. After 3 months treatment with prednisone 10mg daily and Symbocort (4.5ug/160ug) 2 puff twice a day, expectorants and controlling glucose levels, his symptom improved and the chest CT scan returned to normal.
DISCUSSION: It can be hypothesized that intense thermal stimulation of the bronchial mucosa may cause the recurrence of bronchial inflammation, infection and plugging in susceptible patients, especially with diabetes mellitus, and then attribute to the the form of central bronchiectasis.
CONCLUSIONS: It remains unclear why this patient developed bronchiectasia after BT treatment. As the procedure becomes more widely available, It is important to pay attention for the short-term and long term safety data post BT treatment.
Reference #1: Cox G, Thomson NC, Rubin AS, et al. Asthma control during the year after bronchial thermoplasty[J]. N Engl J Med, 2007, 356(13):1327-37.
DISCLOSURE: The following authors have nothing to disclose: Qingling Zhang, Jiaxing Xie, Rihuang Qiu, Zhengdao Lai, Shiyue Li
No Product/Research Disclosure Information
Become a CHEST member and receive a FREE subscription as a benefit of membership.
Individuals can purchase this article on ScienceDirect.
Individuals can purchase a subscription to the journal.
Individuals can purchase a subscription to the journal or buy individual articles.
Learn more about membership or Purchase a Full Subscription.
Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited:
Customize your page view by dragging & repositioning the boxes below.
Enter your username and email address. We'll send you a reminder to the email address on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.