SESSION TITLE: Occupational and Environmental Lung Diseases
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: Occupational inhalation of dust, such as asbestos or crystalline silica, for prolonged periods in the workplace leads to fibrotic lung diseases worldwide. We have previously showed that FSTL1, a secreted extracellular glycoprotein, is a profibrotic factor that is up-regulated in lungs of patients with IPF and bleomycin-injured mouse model. The role of FSTL1 in the development of other fibrotic lung diseases, such as asbestosis, pneumoconiosis and silicosis, is currently unknown.