0
Obstructive Lung Diseases: COPD Phenotypes |

Exploratory Study of the Clinical Phenotypes of Obstructive Disease by Two-Step Cluster Analysis

Pu Ning, MA; Yanfei Guo, PhD
Author and Funding Information

Beijing Hospital, Beijing, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A396. doi:10.1016/j.chest.2016.02.411
Text Size: A A A
Published online

Extract

SESSION TITLE: COPD Phenotypes

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To explore the clinical phenotypes of airways disease by two-step cluster analysis.

METHODS: A population sample of adults who had wheeze within the last 12 months underwent detailed investigation, includingaclinical questionnaire, pulmonary function tests, blood tests (total serum IgE levels and blood eosinophil level) anda peak flow diary. Cluster analysis was carried out on the data set with the subjects defined as described using the following nine variables: 1) pre-bronchodilator FEV1/FVC ratio expressed as a percentage; 2) pre-bronchodilator FEV1 expressed as a percentage of the predicted value; 3) post-bronchodilator change in FEV1, expressed as percentage from baseline; 4) residual capacity expressed as a percentage of the predicted value; 5) diffusing capacity of the lung for carbon monoxide/alveolar volume adjusted for haemoglobin level and expressed as a percentage of the predicted value; 6) the variability of PEF; 7) the serum IgE level; 8) cumulative tobacco cigarette consumption; 9) respiratory symptoms.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543