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Obstructive Lung Diseases: COPD Pharmacotherapy |

The Efficacy of CSL in COPD Patients Exacerbations Treated With or Without Inhaled Steroids

Gregorino Paone, MD; Luigi Lanata, MD; Federico Saibene, MD; Barbara Moscatelli, MD; Renato Delli Colli, MD; Augusto Bevilacqua, MD; Giovanni Puglisi, MD
Author and Funding Information

Dompé Farmaceutici, Milan, Italy


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A392. doi:10.1016/j.chest.2016.02.407
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SESSION TITLE: COPD Pharmacotherapy

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Chronic obstructive pulmonary disease (COPD) is a progressive disease that makes it hard to breathe. It is characterized by mucus alterations, airway inflammation and oxidative stress contributing to corticosteroid resistance. Carbocysteine lysine salt monohydrate (CLS) is a mucoactive drug efficacy in the treatment of bronchopulmonary diseases including COPD. The PEACE study showed a reduction of 25% of exacerbations for patients treated with carbocysteine in COPD. However, only 17% of PEACE study patients received background therapy including inhaled steroids (IS).

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