SESSION TITLE: COPD: Etiology
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: Cigarette smoke (CS) is a highly complex mixture and many of its components are known carcinogens, mutagens, and other toxic substances, whici is associated with an increased incidence of chronic obstructive pulmonary disease (COPD). In this study, we hypothesized that Irbesartan, an angiotensin receptor blockade, protected against cigarette smoke extract-induced apoptosis of A549 human lung carcinoma cells by inducing the expression of Nrf2.