SESSION TITLE: COPD: Etiology
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: Sulforaphane (SFN) is a natural isothiocyanate that is present in cruciferous vegetables such as broccoli and cabbage. Previous studies have shown that SFN is effective in preventing inflammation. The aim of this study is to test the the anti-inflammatory effect of SFN on LPS or Pam3CSK4-stimulated inflammation through inhibiting TLRs/MyD88 pathway in monocyte-derived macrophages (MDM) derived from chronic obstructive pulmonary disease (COPD) patients.