SESSION TITLE: COPD
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Sunday, April 17, 2016 at 09:45 AM - 11:15 AM
PURPOSE: The purpose of this study was to evaluate the effectiveness of NIV as rescue therapy in relieving exertional dyspnea in stable severe COPD patients.
METHODS: This was a randomized crossover study in 18 male patients with stable severe-to-very severe COPD (mean ± SD FEV1: 29.5 ± 6.9% predicted). Exertional dyspnea was induced with maximal symptom-limited incremental cycle exercise. Then the patients would randomly receive oxygen therapy or NIV plus oxygen therapy. Patients were crossed to another therapy group in the second day. During the whole process, HR, SpO2 and breathing pattern were monitored continuously until complete recovery. At every 30s interval, inspiratory capacity (IC) and severity of dyspnea (Borg scale) were assessed. Changes in IC, ventilation, breathing pattern, dyspnea intensity and total dyspnea recovery time were compared between two interventions.