Lung Cancer: Thoracic Malignancies |

Primary Tracheal Mucosal-Associated Lymphoid Tissue Lymphoma: A Case Report and Literature Review FREE TO VIEW

Wen Yin, MD; Li Yuan, MD; Yi Hu, MD; Su Zhao, MD
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The Central Hospital of Wuhan, Wuhan, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A335. doi:10.1016/j.chest.2016.02.348
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SESSION TITLE: Thoracic Malignancies

SESSION TYPE: Case Report Slide

PRESENTED ON: Sunday, April 17, 2016 at 04:00 PM - 05:00 PM

INTRODUCTION: Primary tracheal mucosal-associated lymphoid tissue (MALT) lymphoma is extremely rare. We report another case and analyzed the published cases to summarize the clinical characteristics and experiences in the diagnosis and treatment.

CASE PRESENTATION: This report described a case of primary tracheal MALT lymphoma in a 57-year-old female who presented with wheezing, and the airway tumor was removed by bronchoscopic interventional therapy. Additionally, we reviewed published cases and analyzed the clinical characteristics, diagnosis, treatment and prognosis of tracheal MALT lymphoma.

DISCUSSION: Primary tracheal MALT lymphoma was rare and most of the published literatures were case reports, and 76.2% of all these patients were female with an average age of 57.7 years (range from 21years to 83 years). Clinical symptoms were atypical, including hoarseness, cough, wheezing, dyspnea and hemoptysis. In these cases, 68.2% of imaging tests showed single or multiple intraluminal nodules. The outcome and prognosis of tracheal MALT lymphoma was good and this disease responsed favourably to traditional treatment such as surgery, radiotherapy and chemotherapy, as well as interventional therapy by bronchoscopy.

CONCLUSIONS: Primary tracheal MALT lymphoma is an uncommon airway tumour with favourable prognosis, bronchoscopic interventional therapy could be a valuable strategy for treament.

Reference #1: Cohen SM, Petryk M, Varma M, et al. Non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue. Oncologist 2006;11:1100-1117

Reference #2: Isaacson P, Wright DH. Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma. Cancer 1983;52:1410-1416

Reference #3: Fidias P, Wright C, Harris NL, et al. Primary tracheal non-Hodgkin's lymphoma. A case report and review of the literature. Cancer 1996;77:2332-2338

DISCLOSURE: The following authors have nothing to disclose: Wen Yin, Li Yuan, Yi Hu, Su Zhao

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