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Lung Cancer: Lung Cancer III |

The Role of NY-ESO-1 Activated Dendritic Cell Vaccines in Treating Advanced Non-small Cell Lung Cancer

Yu Dan; Jianli Tang; Qiasheng Li; Huanhuan Zhang; Chengzhi Zhou; Runhui Zheng; Jun Xu
Author and Funding Information

State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A313. doi:10.1016/j.chest.2016.02.326
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SESSION TITLE: Lung Cancer III

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Immunotherapy is emerging as a major modality in treating non-small cell lung cancer (NSCLC) that is not sensitive to traditional anti-cancer therapies. Because of poor immunogenicity and heterogeneity of NSCLC, there is no international recognition of the DC vaccine. NY-ESO-1 is one of the most potential antigens within all testicular Cancer antigens and because of epitope spreading, vaccines against NY-ESO1 may also lead to a development of immune responses against other antigens. So our study is aimed to develop a new model of clinical immunotherapy with NY-ESO-1 sensitized DC vaccines.

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