SESSION TITLE: Lung Cancer II
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: To investigate the role of Focal Adhesion Kinase (FAK) in angiogenesis of pulmonary malignant tumor in vivo and in vitro.
METHODS: We detected the expression of FAK in human umbilical vein endothelial cells (HUVECs), and we used TAE226, FAK siRNA and analyzed their inhibitory effects on HUVECs in vitro. Tumor xenografts in nude mice were used to examine the in vivo activity of TAE226 and FAK siRNA.