SESSION TITLE: Lung Cancer II
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: To further investigate the adverse role of LncRNA in the NSCLC.
METHODS: We screened the expression of LncRNA in two NSCLC lines, 95D and 95C with high and low metastatic potential respectively, using the high throughput LncRNA chip and identified high expression of TATDN1, one of lncRNAs, in the 95D cells comparing with low expression of TATDN1-1 in 95C cells. Then RNA interference (RNAi) was used to block TATDN1expression in 95D cells and the cell proliferation, adhesion, migration and invasion of the TATDN1 depleted 95D cells were investigated.