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Lung Cancer: Lung Cancer I |

Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma: Analysis of 13 Patients FREE TO VIEW

Qiuhong Li
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Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A298. doi:10.1016/j.chest.2016.02.311
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SESSION TITLE: Lung Cancer I

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To study the clinical manifestations and radiological characteristics, diagnostic methods of 13 pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma in China.

METHODS: A retrospective review of clinical, radiological and follow-up data of 13 pulmonary MALT lymphoma cases at Shanghai Pulmonary Hospital affiliated to Tong Ji University from January 2009 to September 2012 was performed.

RESULTS: Among these patients, there were 10(76.9%) males and 3(23.1%) females aged from 37 to 76 (median 57) years old. Common clinical manifestations were cough (9,69.2%), apnea (3,23.1%), bloody sputum 2(15.4%), while 2(15.4%) cases had no symptoms at diagnosis. The characteristics of the chest CT showed: the lesions were characterized by multiple consolidation shadows with air bronchogram sign (n = 10), multiple nodules (n = 2), solitary mass (n = 1). Seven (53.8%) cases were confirmed by surgery 4 (30.8%) by percutaneous lung biopsy, 2 (15.4%) by bronchoscopic biopsy. In some cases the presence of immune deficiencies cells, blood CD4 decreased in six cases. Blood tumor markers normal nine cases, four cases of abnormal, CYFRA21-1 increased in two cases, CA72-4 and CA199 increased in 1 case. The treatment methods included surgery, combined chemotherapy, radiotherapy and Chinese herbal medicine.

CONCLUSIONS: Pulmonary MALT lymphoma is atypical in clinical manifestations and easy to be misdiagnosed. The typical features of CT was consolidation shadows with air bronchogram sign. It may be associated with cell-related immune deficiency. The blood tumor markers in patients with non-specific increased. A proper diagnosis is mainly based on pathological biopsy.

CLINICAL IMPLICATIONS: The typical features of CT was consolidation shadows with air bronchogram sign. If we grasp the characteristics of chest CT, we can gives more accurate diagnosis at the first time.

DISCLOSURE: The following authors have nothing to disclose: Qiuhong Li

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