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Lung Cancer: Late-Breaking Abstracts: Lung Cancer Mechanisms |

Detection of FHIT in Non-small Cell Lung Carcinomas: Correlation With Clinicopathologic Parameters

Ioannis Sfiniadakis, MD; Evdokia Sfiniadaki, MDS; Dimitra Vasileiou-Dervisoglou, MD; Fotios Psarros, MD; Ekaterini Politi, MD
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Athens Naval Hospital, Keratsini, Greece


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A259. doi:10.1016/j.chest.2016.02.271
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SESSION TITLE: Late-Breaking Abstracts: Lung Cancer Mechanisms

SESSION TYPE: Original Investigation Slide

PRESENTED ON: Sunday, April 17, 2016 at 08:30 AM - 09:30 AM

PURPOSE: The purpose of this study is the expression of FHIT in non small cell lung carcinomas and its relationship with clinicopathologic parameters.

METHODS: We studied tissue sections of 84 patients, 48 - 81 years old (mean age 62.3 years) from the file of Surgical Pathology Department of Athens Naval Hospital with primary non small cell lung carcinoma (44 squamous cell carcinomas, 40 adenocarcinomas, 50 smokers, 34 non smokers). We used the immunohistochemical method avidin-biotin-peroxidase after the pretreatement of the slides in microwave with citrate buffer 10mmol / L, ph:6.0. The polyclonal antibody anti-FHIT 1: 50 dilution was used (incubation time 1 hour in room temperature)

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