SESSION TITLE: Late-Breaking Abstracts: Lung Cancer Mechanisms
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Sunday, April 17, 2016 at 08:30 AM - 09:30 AM
PURPOSE: Cigarette smoking is the most important risk factor of lung cancer, and greater than 90% of lung cancers are cigarette smoke-related. Recent studies have indicated that the RNA-binding motif protein 5 (RBM5) has the ability to suppress tumor growth. The aim of this study was to investigate the role of RBM5 in cigarette-smoke extract (CSE)-induced cancerous transformation of bronchial epithelial cells and its regulation mechanism.