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Genetic and Developmental Disorders: Genetic Disorders |

Association of ADAM33 Gene Polymorphisms With Chronic Obstructive Pulmonary Disease in Han Population of Northern China

Ruijun Qin; Ping Wang
Author and Funding Information

Taiyuan City Central Hospital, Taiyuan, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A246. doi:10.1016/j.chest.2016.02.256
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SESSION TITLE: Genetic Disorders

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To investigate whether polymorphisms and haplotypes in ADAM33 gene are associated with chronic obstructive pulmonary disease (COPD) and lung function in Han population of northern China.

METHODS: The genotypes of S1, S2, BC+1, F+1, M + 1 and Q1 locus alleles in 100 COPD patients and 100 healthy controls were tested with PCR-direct sequeneing analysis. Haplotypes and their frequencies were established and analyzed by SHEsis online software.

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