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Diffuse Lung Disease: Diffuse Lung Disease: Interstitial Lung Disease |

Mice Alveolar Epithelial Cells Phenotype Changed by NMDA Receptors Activation

Yang Li, PhD; Fei-Yan Zhao; Wei Liu; Yan-Hong Huang; Chen Li; Dan-Dan Feng; Jian-Zhong Han; Zi-Qiang Luo
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Central South University, Changsha, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A216. doi:10.1016/j.chest.2016.02.223
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SESSION TITLE: Diffuse Lung Disease: Interstitial Lung Disease

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Pulmonary fibrosis is a sever disease which threaten human health, with progressing myofibroblast proliferation, extracellular matrix accumulation. Epithelial-mesenchymal transition (EMT) is an important resource of myofibroblast in pulmonary fibrosis. We had found that NMDA receptors participated in bleomycin induced acute lung injury. We aimed to find out whether NMDA receptors activation contributes to EMT.

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