CASE PRESENTATION: A 16-year-old girl with Hodgkin’s Lymphoma under chemotherapy including bleomycin (accumulative dose of 90 units) was admitted with fever and dyspnea. Patient’s temperature was 39.5o C with 22 breaths/minute, SpO2 92% (FiO2 21%), heart rate 140 beats/minute, arterial pressure 110/70 mmHg and fine bibasilar crepitations. Echocardiogram was normal. Chest radiograph showed patchy consolidations in the left lung base. Blood white cells and neutrophils count were normal. C-reactive protein was 11.4 mg/dl, hematocrit 28, 2%, hemoglobin 9, 33 gr/dl, and Erythrocyte Sedimentation Rate 106 mm. Blood cultures and urinary antigen tests for Pneumococcus and Legionella were negative. The patient was treated as CAP with Moxifloxacine and Trimethoprime/Sulphamethoxazole. However, the patient’s clinical status deteriorated. Fever did not respond to the applied antibiotic therapy. Dyspnea and tachypnea worsen (breaths 40/min, SpO2 95% on FiO2 60%), and platypnea developed. On the 3rd hospitalization day, chest computerized tomography (CCT) showed bilateral diffuse ground glass opacities affecting all lung fields and paraspinal bibasilar consolidations. No findings of pulmonary embolism were observed. Based on CCT findings along with clinical deterioration under antibiotics, BIP became the first diagnostic choice. The patient was treated with Prednizolone 1 mg/Kgr body weight with immediate dramatic improvement. Seven days later the patient was discharged without any symptoms and signs. Steroids were gradually tapered. Six years later the patient is in excellent condition.