SESSION TITLE: Late-Breaking Abstracts: Clinical Pulmonary and Critical Care Medicine
SESSION TYPE: Original Investigation Slide
PRESENTED ON: Sunday, April 17, 2016 at 01:00 PM - 02:00 PM
PURPOSE: Malignant pleural effusion (MPE) is a common complication of lung cancer. Currently, no specific cure exists for MPE and palliative intervention is the only existing option. Angiogenesis and vascular permeability play a key role in the progress of MPE. Chloroquine (CQ) has been shown to induce vascular normalization. The aim of this study was to assess whether CQ has an effect on MPE in mice by blocking angiogenesis and further explore the mechanism of this treatment.