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Critical Care: Critical Care |

The Job Syndrome Doing a Lethal Job

Hammad Arshad, MD; Rajashekar Adurty, MD; Meilin Young, MD
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Allegheny General Hospital, Pittsburgh, PA


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A136. doi:10.1016/j.chest.2016.02.142
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SESSION TITLE: Critical Care

SESSION TYPE: Case Report Poster

PRESENTED ON: Sunday, April 17, 2016 at 11:45 AM - 12:45 PM

INTRODUCTION: Hyper IgE syndrome is a primary immunodeficiency disorder characterized by recurrent infection of the skin and the lung (1).

CASE PRESENTATION: A 30-year-old African American male with past medical history of Job syndrome, recurrent pulmonary infections, pneumatoceles and cutaneous abscesses presented to our hospital with severe septic shock, DIC and multi-organ failure. A CT of the neck and chest showing small cutaneous abscess in the neck and cavitory lesion in the lung with multi-lobar involvement. The patient was intubated for Acute Respiratory Failure and started on vasopressor support and broad spectrum antibiotics. Further interventions and workup included drainage of the neck abscess and Echocardiogram that was negative for vegetations. Unfortunately, patient was septic with beta hemolytic streptococci bacteremia that didn’t respond to appropriate antibiotics. He eventually died of multiorgan failure

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