RESULTS: The most common nonspecific symptoms were fever, malaise, weight loss and anemia. The most common specific symptoms were sore throat, pharyngeal and laryngeal lump, hoarseness, mucosal ulceration and multiple cervical and armpit lymphadenopathies. CD4 and CD8 lymphocyte counts, and the ratio of CD4/CD8 were decreased in all patients. Electronic laryngoscopy indicated pharyngeal ulcers and/or lumps. Penicillium marneffei was isolated from blood samples (2/2) and pharyngeal lesion tissue (6/6). All patients in our retrospective analysis were positive for Penicilliosis marneffei infection by histopathology of pharyngeal tissue samples.