RESULTS: 78 cases were enrolled in total in the study, among which there were 40 cases of candida, 25 cases of aspergillus, 8 cases of Cryptococcus, 1 case of mucor and 4 cases of unclassified ones. There were 33 cases of pulmonary fungal infection. Underlying diseases combined with fungal infection were as follows successively: 35 cases of cardia-cerebrovascular diseases, 20 cases of endocrine system disease, 16 cases of respiratory diseases and 13 tumors. Most candida invasive infections take the form of candidemia (77.5%). Death rate of 40 cases of invasive candidal infections was 50%. There were 25 cases of pulmonary aspergillus infection, the clinical manifestation of which were mainly hemoptysis, cough, fever accompanied with symptoms of dyspnea and expectoration.