SESSION TITLE: Chest Infections: Bronchieactasis
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: Pseudomonas aeruginosa (P. aeruginosa) confers significant adverse impacts on bronchiectasis, in which excessive matrix metalloproteinases (MMPs) release contributes to abnormal bronchial dilatation. We aimed to compare airway MMPs levels, derived from sputum and bronchial mucosa, in bronchiectasis based on sputum bacteriology; the incidence of and time to BEs when stratified by P. aeruginosa infection and MMPs levels; changes in MMPs during bronchiectasis exacerbations (BEs) in patients with or without chronic P. aeruginosa infection.