SESSION TITLE: Chest Infections
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: The possibility exists for an influenza pandemic, and new treatments are needed. We postulated that hydrogen peroxide generated by pharmacologic vitamin C had antiviral properties.
METHODS: Ascorbate was analyzed with HPLC and H2O2 was measured by Clark electrode. NHBE cells infected with virus were treated with ascorbic acid, then harvested to determine virus titer. BALB/c mice infected intranasally with influenza virus were treatments with ascorbic acid, and lung were havested for viral titration and histopathologic evaluation