Chest Infections: Chest Infections |

Analysis of Clinical Characteristics of 3 Cases of Human Infection With H7N9 Avian Influenza Virus in the Same Town for 3 Consecutive Years FREE TO VIEW

Zhoufang Mei, MMed
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The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China

Copyright 2016, American College of Chest Physicians. All Rights Reserved.

Chest. 2016;149(4_S):A82. doi:10.1016/j.chest.2016.02.087
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SESSION TITLE: Chest Infections

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To review and discussion of human infection with highly pathogenic H7N9 etiology characteristics of avian influenza virus, epidemiology, clinical characteristics and treatment method, in order to reduce their misdiagnosis and incorrect treatment.

METHODS: The clinical data of 3 cases of human infected with H7N9 avian influenza in our hospital from the early time of 2013 to the later time of 2014 for 2 consecutive years were analyzed retrospectively, and the related literatures were reviewed.

RESULTS: In 3 patients the incidence area for the same area; all the time for the beginning of each year in winter; 3 patients were male, the age distribution of young, middle-aged, elderly, among which 1 case had history of exposure to poultry, 2 cases had no history of exposure to poultry; of which 1 case had underlying diseases, 2 patients without underlying diseases; 3 cases were acute onset, all cases had fever; 2 case imaging showed patchy exudation and consolidation, 1 cases showed interstitial changes; imaging of two lungs were involvement; 2 cases were throat specimens positive by PCR detection results of progeny viruses; 1 case was diagnosed by the anti-body positive; laboratory of gene sequencing were different in 2 cases of virus; drug sensitivity for virus in laboratory was all for oseltamivir in 3 patients; prognosis for death; close contacts of all the 3 patients without infection

CONCLUSIONS: Clinical manifestation for fever, cough, less sputum or yellow sputum, headache, myalgia and systemic discomfort symptoms, especially at initial stage of the course, the temperature continued in more than 39 degrees, also associated with dyspnea, hemoptysis.

CLINICAL IMPLICATIONS: When imaging for multiple effusion, pleural effusion, pulmonary changes, white blood cell count normal or decreased, or lymphocyte count reductions of the patients, Doctors should be highly vigilant H7N9 virus infection in respiratory, tract virological examination as soon as possible, make sure early detection, early treatment and reduce misdiagnosis and mistreatment.

DISCLOSURE: The following authors have nothing to disclose: Zhoufang Mei

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