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Chest Infections: Chest Infections |

A 4-Year Retrospective Analysis of Nosocomial Infection and Risk Factors in Tumor Radiotherapy Department FREE TO VIEW

Yuan Niu, MMed; Jian Li, MMed; Hong Chen, MMed; Chun Zheng, MMed
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The First Affliated Hospital, Sun Yat-sen University, Guangzhou, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A78. doi:10.1016/j.chest.2016.02.083
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SESSION TITLE: Chest Infections

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: To analyze the feature of nosocomial infection in patients with malignant tumor after radiotherapy. Besides, to investigate the risk factors of them, so as to provide guidance for clinical treatment.

METHODS: The clinical data of 65 patients who underwent radiotherapy in our hospital from 2011 to 2014 were retrospectively analyzed, then the incidence of nonsocial infections, infection sites, distribution of pathogens, and risk factors were taken for statistics, and the statistical analysis of all the data was performed using SPSS 19.0 software.

RESULTS: 2136 patients were treated in 4 years, and 65 patients acquired nonsocial infection with the infection rate of 3.04%. The top three infection sites were respiratory tract, urinary tract and gastrointestinal tract, and the infection rates were 45.84%, 22.22% and 12.50%, respectively. 68 pathogens were isolated, with 44 stains of gram negative bacteria (64.71%), 15 stains of gram positive bacteria (22.06%) and 9 stains of fungi (13.24%). Among them, the infection rate of Antibacterial Badman was the highest (32.35%). There were seven risk factors of nonsocial infection, including, elderly (over 65 years), once infection in the previous 3 months, white blood cell count decreased (<1.5*109/L), longer hospitalization days (equal to or more than 30 days), broad-spectrum antibiotic use for a long time (more than or equal to 7 days), recently received immunosuppressive therapy and the patients underwent invasive operation, respectively. Hospitalization days were equal to or more than 30 days with the maximum OR value (19.069), which was the main influence factor for the nonsocial infection.

CONCLUSIONS: The patients with low immune function were easily occurred to nonsocial infection after radiotherapy. We must strengthen the pathogen monitoring and management. Because of the risk factors for patients with nonsocial infection were various, we should take corresponding preventive and treatment strategies for them, so as to effectively control the nonsocial infection rate.

CLINICAL IMPLICATIONS: The department of tumor radiotherapy is not optimistic in recent years about nonsocial infection prevention and control. On the one hand, we need to monitor the infection sites and pathogens. On the other hand, we should carry out key protection, establish strict disinfection and isolation system, shorten the length of hospital stay, prevent the abuse of antibiotics, carry out publicity and education of hospital infection, about the risk factors of hospital infection.

DISCLOSURE: The following authors have nothing to disclose: Yuan Niu, Jian Li, Hong Chen, Chun Zheng

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