0
Chest Infections: Chest Infections |

The Diagnostic Efficacy and Safety of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Intrathoracic Tuberculosis: A Meta-analysis FREE TO VIEW

Wu Ye, MD; Ke Ying, MD
Author and Funding Information

Sir Run Run Shaw Hospital, Hangzhou, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A74. doi:10.1016/j.chest.2016.02.079
Text Size: A A A
Published online

SESSION TITLE: Chest Infections

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive technique. A meta-analysis was performed to assess efficacy and safety of EBUS-TBNA for intrathoracic tuberculosis (TB).

METHODS: We retrieved Pubmed, Cochrane Library and Web of Science for suitable studies. The pooled sensitivity, specificity, likelihood ratios and diagnostic odds ratio (DOR) were calculated. The summary receiver operator characteristic (SROC) curve was constructed to calculate the area under the SROC curve and Q point value (Q*).

RESULTS: A total of eight studies with 809 patients were included. The pooled sensitivity and specificity of EBUS-TBNA in diagnosis of intrathoracic TB was 0.80 (95%CI, 0.74-0.85) and 1.00 (95% CI, 0.99-1.00). The positive likelihood ratios (PLR) was 38.25 (95% CI, 13.59-107.65), the negative likelihood ratios (NLR) was 0.24 (95% CI, 0.17-0.33), and the DOR was 186.35 (95% CI, 63.57-546.28). The area under the SROC curve was 0.935 and the Q* was 0.871. The pooled sensitivity of EBUS-TBNA in diagnosis of intrathoracic tuberculous lymphadenopathy was 0.87 (95% CI, 0.80-0.95). Only one serious complication was reported.

CONCLUSIONS: EBUS-TBNA is an effectively and safely diagnostic tool for intrathoracic TB, especially for intrathoracic tuberculous lymphadenopathy.

CLINICAL IMPLICATIONS: EBUS-TBNA is an effectively and safely diagnostic tool for intrathoracic TB, especially for intrathoracic tuberculous lymphadenopathy.

DISCLOSURE: The following authors have nothing to disclose: Wu Ye, Ke Ying

No Product/Research Disclosure Information


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543