RESULTS: Out of 694 PTB patients, 606 (87.3%) were diabetic and 88 (12.7%) were non-diabetic. Most of the patients in both groups (71.1% DM vs 63.6% non-DM) were male. Compared to non-DM patients, patients with DM were older (Mean age 48.7±12.4 vs 36.4±17.0; p=0.015] and had increased body mass index (BMI) (Mean BMI 20.0±3.7 vs 18.4±3.3; p=0.003). There was no significant difference in the clinical features of PTB (fever 96.4% vs 94.3%, cough 92.0% vs 95.5%, weight loss 87.8% vs 85.2% respectively) between DM and non-DM patients. Compared to non-DM patients, cavitary lesion (26.7% in DM vs 8.0% in non-DM) and lower-lobe opacity (28.3% in DM vs 14.9% in non-DM) in chest x-ray were more in diabetics whereas apical opacity (1.7% in DM vs 5.7% in non-DM) and pleural effusion (9.3% in DM vs 12.6% in non-DM) was more in non-DM [p=0.000]. Most of the DM patients (60.1%) had sputum smear positive PTB while non-DM patients (66.7%) had smear negative PTB. Gene x-pert MTB/RIF was positive more in DM patients (93.7% vs 88.6%) [p=0.05].