SESSION TITLE: Asthma III
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE: The cytokines IL-33, thymic stromal lymphopoietin (TSLP) and IL-25 have been implicated in asthma pathogenesis owing to the ability to promote Th2-type cytokine synthesis, but their relative importance in “real-life” human asthma is unclear. In the present study, using bronchial alveolar lavage fluid (BALF) as window we aimed to examine airways concentrations of these mediators, along with those of Th1- and Th2-type cytokines in a large group asthmatics (n=70) and controls (n=30), and in the asthmatics compare their concentrations with those of Th1- and Th2-type cytokines, global IgE synthesis and lung function.