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Allergy and Airway: Asthma III |

Dynamic Analysis of Accumulation of Type 2 Innate Lymphoid Cells in Tissues and Organs in IL-25 and IL-33-Induced Murine Models of Asthma

Yan Li; Zhe Lv; Jingjing Wang; Yafei Chi; Ping Huang; Chris Corrigan; Kewu Huang; Wei Wang; Sun Ying
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Capital Medical University, Beijing, China


Copyright 2016, American College of Chest Physicians. All Rights Reserved.


Chest. 2016;149(4_S):A27. doi:10.1016/j.chest.2016.02.029
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SESSION TITLE: Asthma III

SESSION TYPE: Original Investigation Poster

PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM

PURPOSE: Type 2 innate lymphoid cells (ILC2) play important role in the pathogenesis of asthma because of producing large amounts of Th2-type cytokines. The mechanisms of ILC2 chemotaxis into lungs, however, are still unclear. We aimed to compare dynamic accumulation of ILC2 into various organs and tissues in IL-25- and IL-33-induced murine models of asthma and to explore the potential mechanisms of ILC2 chemotaxis.

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