SESSION TITLE: Asthma III
SESSION TYPE: Original Investigation Poster
PRESENTED ON: Saturday, April 16, 2016 at 11:45 AM - 12:45 PM
PURPOSE:The role of IL-17A in the pathogenesis of early infection with RSV increasing susceptibility to asthma.
METHODS: Establishing a mice model of immune tolerance by oral feeding with OVA, and infected with RSV before arousing airway high reactivity. Neutralizing IL-17A before infected with RSV. After the last challenge with OVA the mice were analyzed for AHR, eosinophil infiltration, levels of cytokines, IgE production, percentage of Th2 and Th17 cell, and lung histology.